The Human Reference Genome
Source: IRF7⇦⇨ interferon regulatory factor 7
GAAACTCCCGCCTGGCCACCATAAA... Show All
IRF7 encodes interferon regulatory factor
7, a member of the interferon regulatory
transcription factor (IRF) family. IRF7
has been shown to play a role in the transcriptional
activation of virus-inducible cellular genes,
including interferon beta chain genes. Inducible
expression of IRF7 is largely restricted
to lymphoid tissue. Multiple IRF7 transcript
variants have been identified, although
the functional consequences of these have
not yet been established.
Expression of interferon regulatory factor
7 has been detected in lymph node, white
blood cells, spleen, lung, bone marrow and
29 other tissues.
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associated with response to abatacept in
patients with rheumatoid arthritis.
32161340 Adaptations of
Interferon Regulatory Factor 3 with Transition
from Terrestrial to Aquatic Life.
32132203 Circadian control of
interferon-sensitive gene expression in murine
30232186 NSs protein of Sandfly fever Sicilian
phlebovirus counteracts interferon induction by
masking the DNA-binding domain of
interferon regulatory factor 3.
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mitochondrial Apoptotic Pathway in Systemic
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characterisation of NLRX1 in grass carp