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			The Human Reference Genome

  Source:		IRF7


    		interferon regulatory factor 7
     
			GAAACTCCCGCCTGGCCACCATAAA... Show All

			Summary
			IRF7 encodes interferon regulatory factor
			7, a member of the interferon regulatory
			transcription factor (IRF) family. IRF7
			has been shown to play a role in the transcriptional
			activation of virus-inducible cellular genes,
			including interferon beta chain genes. Inducible
			expression of IRF7 is largely restricted
			to lymphoid tissue. Multiple IRF7 transcript
			variants have been identified, although
			the functional consequences of these have
			not yet been established.

			Expression of interferon regulatory factor
			7 has been detected in lymph node, white
			blood cells, spleen, lung, bone marrow and
			29 other tissues.

			Location
			Chromosome 11

			PubMed
			32184788 Duck TRIM32 Functions in IFN-β
			Signaling Against the Infection of H5N6 Highly
			Pathogenic Avian Influenza Virus.

			32164778 Identification of molecules
			associated with response to abatacept in
			patients with rheumatoid arthritis.

			32161340 Adaptations of
			Interferon Regulatory Factor 3 with Transition
			from Terrestrial to Aquatic Life.

			32132203 Circadian control of
			interferon-sensitive gene expression in murine
			skin.

			30232186 NSs protein of Sandfly fever Sicilian
			phlebovirus counteracts interferon induction by
			masking the DNA-binding domain of
			interferon regulatory factor 3.

			30105262 Investigation of MicroRNA in
			mitochondrial Apoptotic Pathway in Systemic
			Lupus Erythematosus.

			30010019 Molecular cloning and functional
			characterisation of NLRX1 in grass carp
			(Ctenopharyngodon idella).

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