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			MedGen

  Source:		MedGen UID: 275595


     		Viral Pathogenesis

			Definition
			A disease state resulting from virus infection.

			Related Concepts
			interferon
			vaccine
			viral load
			viremia
			influenza
			mutant
			encephalitis
			phosphorylation
			neurologic
			influenza
			antiviral
			unable
			SARS-CoV-2
			severe acute respiratory syndrome
			asymptomatic
			mitochondrial
			cancer
			COVID-19

			BioProject
			PRJNA121239 Expression data of influenza A
			infected human macrophages

			PRJNA93365 Gene expression pattern in
			Caco-2 cells following rotavirus infection

			PRJNA406943 Genome-wide analysis of
			herpes simplex virus type 1 (HSV-1) infected
			cells

			PRJNA285918 HBV Infection and DNA
			Stimulation Induce a Unique Innate Immune
			Response in Hepatocytes

			PRJNA388058 Structural basis for human
			respiratory syncytial virus NS1-mediated
			modulation of host responses

			PRJNA115861 The differentially expressed
			genes induced by EV71 infection

			PRJNA177675 The viral and cellular microRNA
			targetome in lymphoblastoid cell lines

			PRJNA106741 Vaccinia E3L mutant virus
			infected HeLa cell lines
			(langl-affy-human-215499)

			PubMed
			32288954 Critical role of cytochrome c1 and
			its cleavage in porcine reproductive and
			respiratory syndrome virus nonstructural protein
			4-induced cell apoptosis via interaction with
			nsp4.

			32275855 Structural and Functional Basis of
			SARS-CoV-2 Entry by Using Human ACE2.

			32265852 Defeat Dengue and Zika Viruses
			With a One-Two Punch of Vaccine and Vector
			Blockade.

			32257173 An evidence-based framework for
			priority clinical research questions for COVID-19.

			32231671 ANP32B Deficiency Protects Mice
			From Lethal Influenza A Virus Challenge by
			Dampening the Host Immune Response.

			32210284 Specific circulating microRNAs
			during hepatitis E infection can serve as
			indicator for chronic hepatitis E.

			32194543 Delineation of Homeostatic Immune
			Signatures Defining Viremic Non-progression in
			HIV-1 Infection.

			32190290 SARS-CoV-2 and COVID-19: The
			most important research questions.

			32150585 Protein Kinase C subtype δ interacts
			with Venezuelan equine encephalitis virus
			capsid protein and regulates viral RNA binding
			through modulation of capsid phosphorylation.

			31190565 MITOCHONDRIAL REACTIVE
			OXYGEN SPECIES CONTRIBUTE TO
			PATHOLOGICAL INFLAMMATION DURING
			INFLUENZA A VIRUS INFECTION IN MICE.

			31179598 Physiological relevance of
			ACOT8-Nef interaction in HIV infection.

			31175661 The detection rate of Human
			Papillomavirus (HPV) in well differentiated
			squamous cell carcinoma and
			keratoacanthoma: is there new evidence for a
			viral pathogenesis of keratoacanthoma?

			31172216 Pancreatic beta cells persistently
			infected with coxsackievirus B4 are targets of
			NK cell-mediated cytolytic activity.

			31161802 Targeting uracil-DNA glycosylases
			for therapeutic outcomes using insights from
			virus evolution.

			31161411 Development of a reverse genetics
			system for Japanese encephalitis virus strain
			SA14-14-2.

			31146743 The interaction of hepatitis B virus
			with the ubiquitin proteasome system in viral
			replication and associated pathogenesis.

			31134099 Impact of Obesity on Influenza A
			Virus Pathogenesis, Immune Response, and
			Evolution.

			31133680 The viral protein corona directs viral
			pathogenesis and amyloid aggregation.

			31130468 Hepatitis E and chronic liver damage
			in apparently immunocompetent individuals:
			Now what?

			31121217 Exploitation of glycosylation in
			enveloped virus pathobiology.

			31112822 Molecular mechanism by which
			residues at position 481 and 546 of measles
			virus hemagglutinin protein define CD46
			receptor binding using a molecular docking
			approach.

			31095749 In silico analysis revealed Zika virus
			miRNAs associated with viral pathogenesis
			through alteration of host genes involved in
			immune response and neurological functions.

			31083694 Roles for E1-independent replication
			and E6-mediated p53 degradation during
			low-risk and high-risk human papillomavirus
			genome maintenance.

			31064833 Authentic Modeling of Human
			Respiratory Virus Infection in Human Pluripotent
			Stem Cell-Derived Lung Organoids.

			31047849 Immunotherapy in hepatocellular
			carcinoma.

			31044455 Identification of potential microRNA
			markers related to Crimean-Congo
			hemorrhagic fever disease.

			31042482 Promiscuous Targeting of Cellular
			Proteins by Vpr Drives Systems-Level
			Proteomic Remodeling in HIV-1 Infection.

			31016795 Long noncoding RNAs: Novel
			regulators of virus-host interactions.

			31011793 Cellular reservoirs of latent
			cytomegaloviruses.

			Clinical Trials
			3388645 Challenge Infection of Healthy Adult
			Volunteers With RSV A2

			2594189 Influenza A H3N2 Human Challenge
			Study in Healthy Adult Volunteers

			2484417 Respiratory Syncytial Virus Human
			Challenge in Healthy Adult Volunteers

			2196961 Adjuvant Therapy of Completely
			Resected Merkel Cell Carcinoma With Immune
			Checkpoint Blocking Antibodies Versus
			Observation

			1973192 Viral Pathogenesis of Early Cystic
			Fibrosis Lung Disease

			1646138 Influenza A 2009 H1N1 Challenge
			Study in Healthy Adults

			271791 Prednisone Treatment for Vestibular
			Neuronitis

			1093 Outcomes of Anti-HIV Therapy During
			Early HIV Infection

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