*ncbi.life
			MedGen

  Source:		MedGen UID: 61674


     		Coronavirus infection

			Definition
			Virus diseases caused by the Coronavirus genus.

			The novel coronavirus causes the illness COVID-19,
			a viral respiratory tract infection. Viral pathogenesis
			and course of illness vary. Most infections are mild
			and may cause symptoms such as cough, congestion,
			fever or chills. Mild weakness, fatigue and joint pain
			(arthralgia) may also occur.

			Life threatening respiratory distress as occurs in
			Acute Respiratory Distress Syndrome (ARDS) and
			Severe Acute Respiratory Syndrome (SARS) is rare
			for individuals under 65 years of age with no other
			conditions. Patients with pre-existing conditions,
			significant comorbidity or respiratory problems
			are at increased risk of serious adverse events.

			Efforts to reduce disease transmission emphasize
			avoiding non-essential interaction with others.

			Contaminated surfaces are known mediators of
			contact transmission. Droplet transmission may
			occur if the viral vector is directly inhaled.

			Reports from Italy indicate that patients currently
			being treated for hypertension may be at greater
			risk of mortality, raising concern that prescription
			of Angiotensin-converting enzyme inhibitor is a
			significant risk factor.

			Cell entry of coronaviruses depends on binding
			of the viral PROS1 spike proteins to the ACE2
			cellular receptor, and processing by the TMPRSS2
			serine protease or CTSB/CTSL cysteine proteases.
			The SARS Coronavirus Protease Pathway can
			be blocked with the serine protease inhibitor
			Camostat and the endosomal cysteine protease
			inhibitor Aloxistatin, see ncbi.life/SARSCOV2DPZ

			The National Institute of Allergy and Infectious Diseases (NIAID)
			is currently conducting clinical trials to identify
			effective therapeutic treatments and protective
			vaccines.

			NIH Grants & Funding
			https://grants.nih.gov

			Related Concepts
			Acalabrutinib (Calquence)
			Anti-MASP-2 Monoclonal Antibody OMS721
			Antiserum product
			APN01
			Baricitinib
			Camrelizumab (SHR-1210)
			Chloroquine (Resochin)
			Complement C5 Inhibitor ALXN1210
			Complement C5 Inhibitor RA101495
			Decernotinib (VX 509)
			Danoprevir
			Eculizumab (Soliris)
			Favipiravir
			Fedratinib
			Heparin
			Hydroxychloroquine (Plaquenil)
			Interferon alfa-2a product
			Interferon alfa-2b product
			Interferon beta-1a product
			Interferon beta-1b product
			Ivermectin
			Lopinavir
			Lopinavir and ritonavir (Kaletra)
			Neutrophil leukocytosis
			Nitazoxanide (Alinia, Daxon)
			Oseltamivir (Tamiflu)
			Peficitinib
			Pirfenidone (Esbriet)
			Plasma Product
			Prednisone (Deltasone)
			Rapivab (Peramivir)
			Remdesivir (GS-5734)
			Ribavirin (Copegus, Rebetol)
			Rintatolimod (Ampligen)
			Ritonavir (Norvir)
			Ruxolitinib (Jakafi)
			Sarilumab
			Siltuximab (Sylvant)
			Tocilizumab (Actemra)
			Tofacitinib (Xeljanz)
			Amprenavir product
			Asunaprevir
			Atazanavir
			Atazanavir response
			Atazanavir sulfate
			Boceprevir
			Boceprevir response
			Brincidofovir
			Cidofovir Anhydrous
			Cidofovir product
			Crixivan
			Cyclopropavir
			Darunavir ethanolate
			Darunavir product
			Feline Infectious Peritonitides
			Fosamprenavir
			Fosamprenavir calcium
			Grazoprevir
			Indinavir Anhydrous
			Indinavir product
			Indinavir sulfate
			Interferon beta
			JNJ-53718678
			Letermovir
			Lopinavir and ritonavir product
			Lopinavir product
			Maribavir
			Middle East respiratory syndrome
			Nelfinavir
			Nelfinavir mesylate
			Nitazoxanide
			Norvir
			Oseltamivir carboxylate
			Oseltamivir phosphate
			Paritaprevir
			Peginterferon alfa-2a response
			Peginterferon alfa-2b response
			Presatovir (GS-5806)
			Ribavarin
			Ribavirin response
			Resochin
			SARS Coronavirus Protease Pathway
			Saquinavir mesylate
			Saquinavir product
			Severe acute respiratory syndrome
			Simeprevir
			Simeprevir response
			Sofosbuvir
			Sofosbuvir response
			Susceptibility to coronavirus 229e
			Taribavirin
			Taribavirin Hydrochloride
			Telaprevir
			Telaprevir response
			Tipranavir
			Tipranavir Disodium
			Viracept
			Viral Breakthrough
			Viral Disease
			Viral Fusion Protein Inhibitors
			Viral Load
			Viral Lower Respiratory Infection
			Viral Pathogenesis
			Viral Pneumonia
			Viral Respiratory Tract Infection
			Viral Upper Respiratory Tract Infection
			Viral Vaccine
			Viral Vector
			Viremia
			Zanamivir product
			SARS-CoV-2
			pneumonia
			infection control
			antiviral
			ground-glass opacity
			crisis

			GenBank
			MN994467 Wuhan seafood market pneumonia
			virus isolate 2019-nCoV/USA-CA1/2020,
			complete genome

			MN988668 Wuhan seafood market pneumonia
			virus isolate 2019-nCoV WHU01,
			complete genome

			MN985325 Wuhan seafood market pneumonia
			virus isolate 2019-nCoV/USA-WA1/2020,
			complete genome

			MN938384 Wuhan seafood market pneumonia
			virus isolate 2019-nCoV_HKU-SZ-002a_2020,
			complete genome

			MN908947 Wuhan seafood market pneumonia
			virus isolate 2019-nCoV Wuhan-Hu-1,
			complete genome

			BioProject
			PRJEB36487 2019_nCoV data generated
			by BGI

			PRJNA603194 Wuhan seafood market
			pneumonia virus

			PRJNA601736 Wuhan seafood market
			pneumonia virus

			PRJNA601630 Wuhan seafood market
			pneumonia virus

			PRJNA350589 HCoV-229E infection of the
			human HuH7 cell line [Experiment B]

			PRJNA350588 Time-course of HCoV-229E
			infection of A549 cells

			PRJNA350587 HCoV-229E infection in A549
			cells: gene regulation in cells adjacent and
			distant to infected cells

			PRJNA350586 HCoV-229E infection of the
			human HuH7 cell line [Experiment A]

			PRJNA118845 Dynamic Innate Immune
			Responses of Human Bronchial Epithelial Cells
			against SARS-CoV and DOHV infection

			PRJNA110347 N-Tera2 differentiated
			human neuronal model: Mock infected
			vs HCoV-OC43 infected

			PubMed
			32346223 Artificial intelligence vs COVID-19:
			limitations, constraints and pitfalls.

			32341946 Chaos game representation dataset
			of SARS-CoV-2 genome.

			32341791 Thoughts on COVID-19 and
			autoimmune diseases.

			32341616 Exploration of alternative supply
			chains and distributed manufacturing in response
			to COVID-19; a case study of medical face
			shields.

			32339971 Pediatric laryngoscopy and
			bronchoscopy during the COVID-19 pandemic:
			A four-center collaborative protocol to improve
			safety with perioperative management strategies
			and creation of a surgical tent with disposable
			drapes.

			32336586 Pharmacotherapy in COVID-19; A
			narrative review for emergency providers.

			32335426 Imaging of coronavirus disease
			2019: A Chinese expert consensus statement.

			32335405 COVID-19 transmission in Mainland
			China is associated with temperature and
			humidity: A time-series analysis.

			32335171 Clinical and epidemiological features
			of COVID-19 family clusters in Beijing, China.

			32335067 Management of Lung Nodules and
			Lung Cancer Screening During the COVID-19
			Pandemic: CHEST Expert Panel Report.

			32335053 Coronavirus disease 2019 (COVID-19)
			in pregnant women: A report based on 116
			cases.

			32334323 Recommendations for triage,
			prioritization and treatment of breast cancer
			patients during the COVID-19 pandemic.

			32333915 Association of Respiratory Allergy,
			Asthma and Expression of the SARS-CoV-2
			Receptor, ACE2.

			32333914 A possible role for B cells in
			COVID-19?: Lesson from patients with
			Agammaglobulinemia.

			32330544 Management of Acute Myocardial Infarction
			During the COVID-19 Pandemic.

			32330439 Connecting clusters of COVID-19:
			an epidemiological and serological investigation.

			32328378 Understanding the Mosaic of
			COVID-19: A Review of the Ongoing Crisis.

			32328219 From Helpless to Hero: Promoting
			Values-Based Behavior and Positive Family
			Interaction in the Midst of COVID-19.

			32325282 Chest CT findings of COVID-19
			pneumonia by duration of symptoms.

			32320852 Déjà vu: Stimulating open drug discovery
			for SARS-CoV-2.

			32320741 Obesity as a risk factor for greater
			severity of COVID-19 in patients with metabolic
			associated fatty liver disease.

			32320740 Low-density lipoprotein is a potential
			predictor of poor prognosis in patients with
			coronavirus disease 2019.

			32318665 Age-related rhesus macaque models
			of COVID-19.

			32318330 Rewriting the rules for care of MDS
			and AML patients in the time of COVID-19.

			32318328 D3Targets-2019-nCoV: a webserver
			for predicting drug targets and for multi-target
			and multi-site based virtual screening against
			COVID-19.

			32318327 Potential therapeutic effects of
			dipyridamole in the severely ill patients with
			COVID-19.

			32317180 Coronavirus Disease 2019 Pneumonia
			in Immunosuppressed Renal Transplant
			Recipients: A Summary of 10 Confirmed Cases
			in Wuhan, China.

			32315881 Mental Health Services in Lombardy
			during COVID-19 outbreak.

			32313879 What are the Underlying Transmission
			Patterns of COVID-19 Outbreak? - An
			Age-specific Social Contact Characterization.

			32313662 Veno-venous extracorporeal
			membrane oxygenation for severe pneumonia:
			COVID-19 case in Japan.

			32313308 COVID-19 and the policy sciences:
			initial reactions and perspectives.

			32312646 Physiotherapy management for
			COVID-19 in the acute hospital setting: clinical
			practice recommendations.

			32312571 Emergency tracheal intubation in
			202 patients with COVID-19 in Wuhan, China:
			lessons learnt and international expert
			recommendations.

			32312290 Salvage use of tissue plasminogen activator
			(tPA) in the setting of acute respiratory distress syndrome
			(ARDS) due to COVID-19 in the USA: a Markov
			decision analysis.

			32311847 COVID-19 Testing in South Korea:
			Current Status and the Need for Faster
			Diagnostics.

			32311448 COVID-19 and Thrombotic or
			Thromboembolic Disease: Implications for
			Prevention, Antithrombotic Therapy, and
			Follow-up.

			32311318 SARS-CoV-2 and viral sepsis:
			observations and hypotheses.

			32309528 Chest CT features and their role in
			COVID-19.

			32307215 Assessing the Burden of Nondeferrable
			Major Uro-oncologic Surgery to Guide
			Prioritisation Strategies During the COVID-19
			Pandemic: Insights from Three Italian
			High-volume Referral Centres.

			32307014 Chinese expert consensus on
			diagnosis and treatment of coagulation
			dysfunction in COVID-19.

			32305831 Flash survey on severe acute respiratory syndrome
			coronavirus-2 infections in paediatric patients
			on anticancer treatment.

			32305557 The impact of 2019 novel coronavirus
			on heart injury: A systemic review and
			Meta-analysis.

			32305402 Disruptive Modifications to Cardiac
			Critical Care Delivery During the Covid-19
			Pandemic: An International Perspective.

			32305075 Endoscopy in inflammatory bowel diseases
			during the COVID-19 pandemic and post-pandemic
			period.

			32303856 Digital triage for people with
			multiple sclerosis in the age of COVID-19
			pandemic.

			32303424 Assessing ACE2 expression patterns
			in lung tissues in the pathogenesis of COVID-19.

			32302782 Pulmonary embolism in patients
			with COVID-19: Time to change the paradigm
			of computed tomography.

			32302401 Targeting potential drivers of
			COVID-19: Neutrophil extracellular traps.

			32292903 COVID-19 infection among
			asymptomatic and symptomatic pregnant
			women: Two weeks of confirmed presentations
			to an affiliated pair of New York City hospitals.

			32292899 Clinical characteristics and outcomes
			of patients undergoing surgeries during the
			incubation period of COVID-19 infection.

			32292881 Coronavirus infections: Epidemiological,
			clinical and immunological features and
			hypotheses.

			32292880 Progress and prospect on imaging
			diagnosis of COVID-19.

			32292689 Analysis of therapeutic targets for
			SARS-CoV-2 and discovery of potential drugs
			by computational methods.

			32291094 Incidence of thrombotic complications
			in critically ill ICU patients with COVID-19.

			32290904 Roll-out of SARS-CoV-2 testing
			for healthcare workers at a large NHS
			Foundation Trust in the United Kingdom, March
			2020.

			32289152 COVID-19 and emerging viral
			infections: The case for interferon lambda.

			32289117 Novel decoy cellular vaccine strategy
			utilizing transgenic antigen-expressing cells
			as immune presenter and adjuvant in vaccine
			prototype against SARS-CoV-2 virus.

			32289115 Care of patients with liver disease
			during the COVID-19 pandemic: EASL-ESCMID
			position paper.

			32289038 A comprehensive Chinese experience
			against SARS-CoV-2 in ophthalmology.

			32284798 How should front-line general
			practitioners use personal protective equipment
			(PPE)?

			32283450 Unprecedented disruption of lives
			and work: Health, distress and life satisfaction
			of working adults in China one month into the
			COVID-19 outbreak.

			32282344 Attending to the Emotional Well-Being
			of the Health Care Workforce in a New York
			City Health System During the COVID-19
			Pandemic.

			32279934 Anesthesia Management and
			Perioperative Infection Control in Patients With
			the Novel Coronavirus.

			32279903 Considerations in the Triage of
			Urologic Surgeries During the COVID-19
			Pandemic.

			32278716 The Restructuring of Structural
			Heart Disease Practice During The Covid-19
			Pandemic.

			32278175 COVID-19: A promising cure for
			the global panic.

			32278065 Diarrhea during COVID-19 infection:
			pathogenesis, epidemiology, prevention and
			management.

			32276755 Infection Control against COVID-19
			in Departments of Radiology.

			32275978 The Role of Chest Imaging in Patient
			Management during the COVID-19 Pandemic:
			A Multinational Consensus Statement from
			the Fleischner Society.

			32275914 Type 1 interferons as a potential
			treatment against COVID-19.

			32274630 Inpatient and outpatient case
			prioritization for patients with neuro-oncologic
			disease amid the COVID-19 pandemic: general
			guidance for neuro-oncology practitioners from
			the AANS/CNS Tumor Section and Society
			for Neuro-Oncology.

			32274570 COVID-19 in the heart and the
			lungs: could we "Notch" the inflammatory
			storm?

			32272957 COVID-19 the showdown for mass
			casualty preparedness and management: the
			Cassandra Syndrome.

			32272396 The possible of immunotherapy for
			COVID-19: A systematic review.

			32269086 Clinical characteristics and outcomes
			of hospitalised patients with COVID-19 treated
			in Hubei (epicenter) and outside Hubei
			(non-epicenter): A Nationwide Analysis of
			China.

			32267678 COVID-19: A Call for Physical
			Scientists and Engineers.

			32265365 Obstetric Anesthesia During the
			COVID-19 Pandemic.

			32265180 Genotype and phenotype of
			COVID-19: Their roles in pathogenesis.

			32265005 Only strict quarantine measures can
			curb the coronavirus disease (COVID-19)
			outbreak in Italy, 2020.

			32259829 COVID-19 Outbreak: An Overview.

			32259628 Clinician Wellness During the
			COVID-19 Pandemic: Extraordinary Times and
			Unusual Challenges for the Allergist/Immunologist.

			32259546 Risk of nosocomial transmission
			of coronavirus disease 2019: an experience
			in a general ward setting in Hong Kong.

			32259130 Epidemiological and Clinical Aspects
			of COVID-19; a Narrative Review.

			32258351 Current knowledge about the antivirals
			remdesivir (GS-5734) and GS-441524 as
			therapeutic options for coronaviruses.

			32253068 Recommendations for
			coronavirus infection in rheumatic diseases
			treated with biologic therapy.

			32248145 Urban Intelligence for Pandemic
			Response: Viewpoint.

			32247013 Guidance for Cardiac Electrophysiology
			During the Coronavirus (COVID-19) Pandemic
			from the Heart Rhythm Society COVID-19
			Task Force; Electrophysiology Section of the
			American College of Cardiology; and the
			Electrocardiography and Arrhythmias Committee
			of the Council on Clinical Cardiology,
			American Heart Association.

			32246819 Pulmonary High-Resolution
			Computed Tomography (HRCT) Findings of
			Patients with Early-Stage Coronavirus Disease
			2019 (COVID-19) in Hangzhou, China.

			32241328 Limited Early Warnings and Public
			Attention to Coronavirus Disease 2019 in
			China, January-February, 2020: A Longitudinal
			Cohort of Randomly Sampled Weibo Users.

			32240718 COVID-19 in Hemodialysis Patients:
			A Report of 5 Cases.

			32240096 Preventive Behaviors Conveyed on
			YouTube to Mitigate Transmission of COVID-19:
			Cross-Sectional Study.

			32238182 The fiscal value of human lives lost
			from coronavirus disease (COVID-19) in China.

			32237287 COVID-19 Testing in South Korea:
			Current Status and the Need for Faster
			Diagnostics.

			32234468 The epidemiology, diagnosis and
			treatment of COVID-19.

			32234451 COVID-19, SARS and MERS: are
			they closely related?

			32232214 Potential Treatments for COVID-19;
			a Narrative Literature Review.

			32231392 Forecasting the novel coronavirus
			COVID-19.

			32227123 Characteristics of peripheral
			lymphocyte subset alteration in COVID-19
			pneumonia.

			32226946 COVID-19: a novel zoonotic disease
			caused by a coronavirus from China: what we
			know and what we don't.

			32226636 Lymphopenia predicts disease
			severity of COVID-19: a descriptive and
			predictive study.

			32226353 The Fear of COVID-19 Scale:
			Development and Initial Validation.

			32226293 The COVID-19 outbreak and
			psychiatric hospitals in China: managing
			challenges through mental health service
			reform.

			32226292 Tribute to health workers in China: A
			group of respectable population during the
			outbreak of the COVID-19.

			32226291 Progression of Mental Health
			Services during the COVID-19 Outbreak in
			China.

			32226286 Zoonotic origins of human
			coronaviruses.

			32219057 The SARS-CoV-2 Vaccine Pipeline:
			an Overview.

			32219006 Modeling the epidemic dynamics
			and control of COVID-19 outbreak in China.

			32218915 National Institute for the Infectious
			Diseases "L. Spallanzani", IRCCS.
			Recommendations for COVID-19 clinical
			management.

			32215365 A nationwide survey of psychological
			distress among Chinese people in the
			COVID-19 epidemic: implications and policy
			recommendations.

			32214942 Diverse gammacoronaviruses
			detected in wild birds from Madagascar.

			32212103 Practical considerations for
			performing regional anesthesia: lessons learned
			from the COVID-19 pandemic.

			32212099 COVID-19 may transmit through
			aerosol.

			32211816 Association of Cardiac Injury With
			Mortality in Hospitalized Patients With
			COVID-19 in Wuhan, China.

			32211279 An Ounce of Prevention:
			Coronavirus (COVID-19) and Mass Gatherings.

			32210742 Role of changes in SARS-CoV-2
			spike protein in the interaction with the human
			ACE2 receptor: An in silico analysis.

			32210483 The Battle Against COVID-19:
			Where Do We Stand Now?

			32210236 Epidemiological data from the
			COVID-19 outbreak, real-time case information.

			32209164 Coronavirus disease (COVID-19) in a
			paucisymptomatic patient: epidemiological and
			clinical challenge in settings with limited
			community transmission, Italy, February 2020.

			32209163 Serological and molecular findings
			during SARS-CoV-2 infection: the first case
			study in Finland, January to February 2020.

			32206052 COVID-19 and smoking: A
			systematic review of the evidence.

			32205937 Is A Problem Shared, A Problem
			Halved? Not Always! The Novel Coronavirus
			COVID-19 Outbreak.

			32203437 Insights from nanomedicine into
			chloroquine efficacy against COVID-19.

			32202646 Factors Associated With Mental
			Health Outcomes Among Health Care Workers
			Exposed to Coronavirus Disease 2019.

			32202421 Can a Paper-Based Device Trace
			COVID-19 Sources with Wastewater-Based
			Epidemiology?

			32202420 An Imperative Need for Research on
			the Role of Environmental Factors in
			Transmission of Novel Coronavirus (COVID-19).

			32199457 Responding to the COVID-19
			pandemic in complex humanitarian crises.

			32196071 Knowledge and Perceptions of
			COVID-19 Among the General Public in the
			United States and the United Kingdom: A
			Cross-sectional Online Survey.

			32195311 From SARS to COVID-19: A
			previously unknown SARS- related coronavirus
			(SARS-CoV-2) of pandemic potential infecting
			humans - Call for a One Health approach.

			32194995 The outbreak of SARS-CoV-2
			pneumonia calls for viral vaccines.

			32191259 Characteristics and Outcomes of 21
			Critically Ill Patients With COVID-19 in
			Washington State.

			32190785 Transmission potential of the
			novel coronavirus (COVID-19) onboard the
			diamond Princess Cruises Ship, 2020.

			32190290 SARS-CoV-2 and COVID-19: The
			most important research questions.

			32189218 The impact of high-flow nasal
			cannula (HFNC) on coughing distance:
			implications on its use during the novel
			coronavirus disease outbreak.

			32189136 Lower mortality of COVID-19 by
			early recognition and intervention: experience
			from Jiangsu Province.

			32189081 AI-Driven Tools for Coronavirus
			Outbreak: Need of Active Learning and
			Cross-Population Train/Test Models on
			Multitudinal/Multimodal Data.

			32189010 Correction to: COVID-19: a
			novel coronavirus and a novel challenge for
			critical care.

			32188484 Host susceptibility to severe
			COVID-19 and establishment of a host risk
			score: findings of 487 cases outside Wuhan.

			32188482 COVID-19 infection epidemic: the
			medical management strategies in Heilongjiang
			Province, China.

			32186278 Influenza-associated pneumonia as
			reference to assess seriousness of
			coronavirus disease (COVID-19).

			32185370 Information Typology in Coronavirus
			(COVID-19) Crisis; a Commentary.

			32185369 Liver and Kidney Injuries in
			COVID-19 and Their Effects on Drug Therapy; a
			Letter to Editor.

			32183935 Retrospective analysis of the
			possibility of predicting the COVID-19 outbreak
			from Internet searches and social media data,
			China, 2020.

			32183934 Post-discharge surveillance and
			positive virus detection in two medical staff
			recovered from coronavirus disease 2019
			(COVID-19), China, January to February 2020.

			32183930 Estimating the asymptomatic
			proportion of coronavirus disease 2019
			(COVID-19) cases on board the Diamond
			Princess cruise ship, Yokohama, Japan, 2020.

			32183901 Epidemiology, causes, clinical
			manifestation and diagnosis, prevention and
			control of coronavirus disease (COVID-19)
			during the early outbreak period: a scoping
			review.

			32183864 Safe patient transport for COVID-19.

			32181302 Application of the ARIMA model on
			the COVID-2019 epidemic dataset.

			32180175 Safety and efficacy of different
			anesthetic regimens for parturients with
			COVID-19 undergoing Cesarean delivery: a
			case series of 17 patients.

			32180173 Lidocaine during intubation and
			extubation in patients with coronavirus disease
			(COVID-19).

			32180157 Brain Awareness Week, CoVID-19
			infection and Neurological Sciences.

			32178711 Treatment of COVID-19: old tricks
			for new challenges.

			32178547 Challenges and Countermeasures of
			Integrative Cancer Therapy in the Epidemic of
			COVID-19.

			32176272 Estimation of Coronavirus Disease
			2019 (COVID-19) Burden and Potential for
			International Dissemination of Infection From
			Iran.

			32176257 COVID-19 and the Risk to Health
			Care Workers: A Case Report.

			32175437 The role of CT for Covid-19 patient's
			management remains poorly defined.

			32175421 Early estimation of the case fatality
			rate of COVID-19 in mainland China: a
			data-driven analysis.

			32175069 Imported Wuhan
			Coronavirus Infection: Is there any Correlation
			with Number of Immigrants from Endemic Area
			and Period after the First Outbreak?

			32174069 Report on the Epidemiological
			Features of Coronavirus Disease 2019
			(COVID-19) Outbreak in the Republic of Korea
			from January 19 to March 2, 2020.

			32174068 Will the Third Wave of
			Coronavirus Disease 2019 Really Come in
			Korea?

			32170953 Limiting spread of COVID-19 from
			cruise ships - lessons to be learnt from Japan.

			32169119 The origin, transmission and clinical
			therapies on coronavirus disease 2019
			(COVID-19) outbreak - an update on the status.

			32167747 Evidence of the COVID-19 Virus
			Targeting the CNS: Tissue Distribution,
			Host-Virus Interaction, and Proposed
			Neurotropic Mechanisms.

			32167524 Risk Factors Associated With
			Acute Respiratory Distress Syndrome and
			Death in Patients With Coronavirus Disease
			2019 Pneumonia in Wuhan, China.

			32166350 [Recommendations for critically ill
			patients with COVID-19].

			32165854 Coronavirus disease-2019: is fever
			an adequate screening for the returning
			travelers?

			32165386 Complete Genome Sequence of a
			2019 Novel Coronavirus (SARS-CoV-2) Strain
			Isolated in Nepal.

			32164708 What further should be done to
			control COVID-19 outbreaks in addition to
			cases isolation and contact tracing measures?

			32163542 Histopathologic Changes and
			SARS-CoV-2 Immunostaining in the Lung of a
			Patient With COVID-19.

			32162212 Preparing for a COVID-19
			pandemic: a review of operating room outbreak
			response measures in a large tertiary hospital in
			Singapore.

			32162211 Chest computed tomography
			images of early coronavirus disease
			(COVID-19).

			32162032 How to balance
			acute myocardial infarction and COVID-19: the
			protocols from
			Sichuan Provincial People's Hospital.

			32160889 Geographical tracking and mapping
			of coronavirus disease
			COVID-19/severe acute respiratory syndrome
			coronavirus 2 (SARS-CoV-2) epidemic and
			associated events around the world: how 21st
			century GIS technologies are supporting the
			global fight against outbreaks and epidemics.

			32160299 Coronavirus Disease 2019
			(COVID-19): Protecting Hospitals From the
			Invisible.

			32160273 How Should U.S. Hospitals Prepare
			for Coronavirus Disease 2019 (COVID-19)?

			32158961 First two months of the 2019
			Coronavirus Disease (COVID-19) epidemic in
			China: real-time surveillance and evaluation with
			a second derivative model.

			32156607 Positive rate of RT-PCR detection of
			SARS-CoV-2 infection in 4880 cases from one
			hospital in Wuhan, China, from Jan to Feb
			2020.

			32156327 First cases of coronavirus disease
			2019 (COVID-19) in the WHO European
			Region, 24 January to 21 February 2020.

			32155789 Immediate Psychological Responses
			and Associated Factors during the Initial Stage
			of the 2019 Coronavirus Disease (COVID-19)
			Epidemic among the General Population in
			China.

			32154287 Chinese expert consensus on the
			perinatal and neonatal management for the
			prevention and control of the 2019 novel
			coronavirus infection (First edition).

			32151274 Preparing for COVID-19: early
			experience from an intensive care unit in
			Singapore.

			32150748 The Incubation Period of
			Coronavirus Disease 2019 (COVID-19) From
			Publicly Reported Confirmed Cases: Estimation
			and Application.

			32149043 Contact Transmission of COVID-19
			in South Korea: Novel Investigation Techniques
			for Tracing Contacts.

			32149037 Early Epidemiological and Clinical
			Characteristics of 28 Cases of
			Coronavirus Disease in South Korea.

			32149036 Identification of Coronavirus Isolated
			from a Patient in Korea with COVID-19.

			32149035 Effectiveness for the Response to
			COVID-19: The MERS Outbreak Containment
			Procedures.

			32144591 What we do when a COVID-19
			patient needs an operation: operating room
			preparation and guidance.

			32139464 The clinical dynamics of 18 cases of
			COVID-19 outside of Wuhan, China.

			32139372 What we know so far: COVID-19
			current clinical knowledge and research.

			32133152 Phase-adjusted estimation of the
			number of Coronavirus Disease 2019 cases in
			Wuhan, China.

			32132744 Data sharing for novel coronavirus
			(COVID-19).

			32132521 The Effects of Social Support on
			Sleep Quality of Medical Staff Treating Patients
			with Coronavirus Disease 2019 (COVID-19) in
			January and February 2020 in China.

			32118389 [Clinical analysis of 31 cases of
			2019 novel coronavirus infection in children
			from six provinces (autonomous region) of
			northern China].

			32114744 [Pregnant women with new
			coronavirus infection: a clinical characteristics
			and placental pathological analysis of three
			cases].

			32112966 2019-novel Coronavirus severe adult
			respiratory distress syndrome in two cases in
			Italy: An uncommon radiological presentation.

			32112508 Spatial association between primary
			Middle East respiratory syndrome coronavirus
			infection and exposure to dromedary camels in
			Saudi Arabia.

			32112072 A Case Series of children with 2019
			novel coronavirus infection: clinical and
			epidemiological features.

			32108352 Clinical trial analysis of 2019-nCoV
			therapy registered in China.

			32107119 Coronavirus Disease 2019:
			Coronaviruses and Blood Safety.

			32102777 The 2019 novel coronavirus
			resource.

			32102279 Assessing the Impact of Reduced
			Travel on Exportation Dynamics of Novel
			Coronavirus Infection (COVID-19).

			32102141 [First case of 2019 novel coronavirus
			infection in children in Shanghai].

			32102140 [Facing the pandemic of 2019 novel
			coronavirus infections: the pediatric
			perspectives].

			32098466 [What are the highlights of
			"Diagnosis and treatment of Disease 2019
			novel coronavirus infection suitable for Military
			support Hubei medical team"].

			32096611 2019 novel coronavirus infection and
			gastrointestinal tract.

			32087334 The epidemic of
			2019-novel-coronavirus (2019-nCoV)
			pneumonia and insights for emerging infectious
			diseases in the future.

			32080991 Viral Load Kinetics of SARS-CoV-2
			Infection in First Two Patients in Korea.

			32079150 Incubation Period and Other
			Epidemiological Characteristics of 2019 Novel
			Coronavirus Infections with Right Truncation: A
			Statistical Analysis of Publicly Available Case
			Data.

			32073213 Abnormal Coagulation parameters
			are associated with poor prognosis in patients
			with novel coronavirus pneumonia.

			32063887 Comprehensive Genomic
			Characterization Analysis of lncRNAs in Cells
			With Porcine Delta Coronavirus Infection.

			32062875 [Retracted: Clinical and
			epidemiological characteristics of 34 children
			with 2019 novel coronavirus infection in
			Shenzhen].

			32061200 [Analysis of CT features of 15
			Children with 2019 novel coronavirus infection].

			32057210 [The prevention and control of a new
			coronavirus infection in department of
			stomatology].

			32052466 Potential Interventions for Novel
			Coronavirus in China: A Systematic Review.

			32050635 Potential Maternal and Infant
			Outcomes from (Wuhan) Coronavirus
			2019-nCoV Infecting Pregnant Women:
			Lessons from SARS, MERS, and Other Human
			Coronavirus Infections.

			32047128 Distinct Roles for Sialoside and
			Protein Receptors in Coronavirus Infection.

			32043842 [2019-novel coronavirus infection in
			a three-month-old baby].

			32036011 Coronavirus infections reported by
			ProMED, February 2000-January 2020.

			32035428 [Suggestions for disinfection of
			ophthalmic examination equipment and
			protection of ophthalmologist against 2019
			novel coronavirus infection].

			32034659 Diagnosis, treatment, and
			prevention of 2019 novel coronavirus infection
			in children: experts' consensus statement.

			32025807 miRNA repertoire and host immune
			factor regulation upon avian coronavirus
			infection in eggs.

			32023680 [Suggestions for prevention of 2019
			novel coronavirus infection in otolaryngology
			head and neck surgery medical staff].

			32023679 [First case of 2019 novel coronavirus
			infection in children in Shanghai].

			32023678 [Facing the pandemic of 2019 novel
			coronavirus infections: the pediatric
			perspectives].

			32013309 Mast cells contribute to
			coronavirus-induced inflammation: new
			anti-inflammatory strategy.

			32009759 Isolation and characterization of
			avian coronavirus from healthy Eclectus parrots
			(Eclectus roratus) from Indonesia.

			32004427 First Case of 2019
			Novel Coronavirus in the United States.

			31999307 The Novel Coronavirus Originating
			in Wuhan, China: Challenges for Global
			Health Governance.

			31987001 Genomic characterization of the
			2019 novel human-pathogenic coronavirus
			isolated from a patient with atypical pneumonia
			after visiting Wuhan.

			31781765 A review of asymptomatic and sub-clinical
			Middle East Respiratory Syndrome
			Coronavirus Infections.

			31769524 Typical epidemiology of respiratory virus
			infections in a Brazilian slum.

			31694960 Murine coronavirus infection activates AhR in an
			IDO1-independent manner contributing to
			cytokine modulation and pro-viral TiPARP
			expression.

			31694947 Three Amino Acid Changes In Avian
			Coronavirus Spike Protein Allows Binding To
			Kidney Tissue.

			31692019 Gold nanoparticle-adjuvanted S protein induces
			a strong antigen-specific IgG response against
			severe acute respiratory syndrome-related
			coronavirus infection, but fails to induce
			protective antibodies and limit eosinophilic
			infiltration in lungs.

			31578288 Small molecule antiviral β-D-N
			4-hydroxycytidine inhibits a proofreading-intact
			coronavirus with a high genetic barrier to
			resistance.

			31234434 Susceptibility of Chickens to Porcine
			Deltacoronavirus Infection.

			31223425 Improved Wound Healing of Airway
			Epithelial Cells Is Mediated by Cold Atmospheric
			Plasma: A Time Course-Related Proteome Analysis.

			31139937 Epidemiology of respiratory viruses
			in Saudi Arabia: toward a complete picture.

			31125806 Nucleoside analogues for the
			treatment of coronavirus infections.

			31113572 Clinical presentation, diagnostic
			findings, and outcome of adult horses with
			equine coronavirus infection at a veterinary
			teaching hospital: 33 cases (2012-2018).

			31094626 Effect of cat litters on feline
			coronavirus infection of cell culture and cats.

			31082732 The ER stress sensor IRE1 and MAP
			kinase ERK modulate autophagy induction in
			cells infected with coronavirus infectious
			bronchitis virus.

			31048107 Differential recognition of peptides
			within feline coronavirus polyprotein 1 ab by
			sera from healthy cats and cats with feline
			infectious peritonitis.

			30984127 Recent Aspects on the
			Pathogenesis Mechanism, Animal Models and
			Novel Therapeutic Interventions for
			Middle East Respiratory Syndrome
			Coronavirus Infections.

			30971240 Analysis of long non-coding RNAs in
			neonatal piglets at different stages of porcine
			deltacoronavirus infection.

			30964454 Epidemiological study of
			Middle East respiratory syndrome
			coronavirus infection in dromedary camels
			in Saudi Arabia, April-May 2015.

			30918074 High-throughput Screening and
			Identification of Potent Broad-spectrum
			Inhibitors of Coronaviruses.

			30914508 Antagonism of dsRNA-Induced
			Innate Immune Pathways by NS4a and NS4b
			Accessory Proteins during MERS Coronavirus
			Infection.

			30882305 Middle East Respiratory Syndrome
			Coronavirus Infection Dynamics and Antibody
			Responses among Clinically Diverse Patients,
			Saudi Arabia.

			30866764 Middle East respiratory syndrome
			coronavirus infection in non-camelid domestic
			mammals.

			30849247 Broad-spectrum coronavirus antiviral
			drug discovery.

			30775355 Absence of neutralizing activity in
			serum 1 year after successful treatment with
			antivirals and recovery from MERS in South
			Korea.

			30658691 Antiviral activity of itraconazole
			against type I feline coronavirus infection.

			30654597 Characterization of the Lipidomic
			Profile of Human Coronavirus-Infected Cells:
			Implications for Lipid Metabolism Remodeling
			upon Coronavirus Replication.

			30626688 TMPRSS2 contributes to virus
			spread and immunopathology in the airways of
			murine models after coronavirus infection.

			30550651 SARS, MERS and coronavirus
			infections.

			28659436 Broad-spectrum antiviral GS-5734
			inhibits both epidemic and zoonotic
			coronaviruses.

			25720466 Coronaviruses: an overview of their
			replication and pathogenesis.

			21994708 Coronavirus genomics and
			bioinformatics analysis.

			21325420 Evidence that TMPRSS2 activates the
			severe acute respiratory syndrome coronavirus
			spike protein for membrane fusion and reduces
			viral control by the humoral immune response.

			16912115 Severe acute respiratory syndrome
			coronavirus nsp1 protein suppresses host gene
			expression by promoting host mRNA degradation.

			17534355 Lack of support for an association
			between CLEC4M homozygosity and
			protection against SARS coronavirus infection.

			17534354 Lack of support for an association
			between CLEC4M homozygosity and
			protection against SARS coronavirus infection.

			16369534 Homozygous L-SIGN (CLEC4M)
			plays a protective role in SARS coronavirus
			infection.

			15809906 Detection of airborne
			severe acute respiratory syndrome
			(SARS) coronavirus and environmental
			contamination in SARS outbreak units.

			15638943 Dynamic changes of serum
			SARS-coronavirus IgG, pulmonary function and
			radiography in patients recovering from SARS
			after hospital discharge.

			12746549 Coronavirus main proteinase (3CLpro)
			structure: basis for design of anti-SARS drugs.

			12690092 A novel coronavirus associated with
			severe acute respiratory syndrome.

			Clinical Trials
			4283461 Safety and Immunogenicity Study of
			2019-nCov Vaccine (mRNA-1273) to Treat
			Novel Coronavirus (Recruiting)

			4280705 Adaptive COVID-19 Treatment Trial
			(Recruiting)

			3615911 Safety, Tolerability and
			Immunogenicity of Vaccine Candidate
			MVA-MERS-S (Completed)

			3233516 Trial of Respiratory Infections in
			Children for Enhanced Diagnostics (Recruiting)

			3277170 Pragmatic RCT of High-dose
			Oral Montelukast for Moderate and Severe Pediatric
			Acute Asthma Exacerbations (Not yet
			recruiting)

			2670187 Phase I, Open Label Dose Ranging
			Safety Study of GLS-5300 in Healthy
			Volunteers (Completed)

			2644135 A Pilot Study of the Safety,
			Tolerability, and Effectiveness of Halo
			(Completed)

			2627378 Saudi Outcomes of ECMO-treated
			MERS-CoV Patients (Completed)

			2203110 The Impact of Simultaneous
			Presence of Viral and Bacterial Pathogens on
			Therapy and Course of Severe Pneumonia
			(Unknown status)

			2190799 Anti-MERS-CoV Convalescent
			Plasma Therapy (Withdrawn)

			2003651 Echinacea and Acute Respiratory
			Illness (Completed)

			1979705 Detect Novel Pathogens and
			Characterize Emerging Infections (Recruiting)

			1546935 Oseltamivir for Influenza Lower
			Respiratory Tract Infection in Children Under
			One (Withdrawn)

			1486160 Respiratory Viral Infection in Nursing
			Home Slovenia (Completed)

			1056354 Respiratory Virus Outpatient Study
			(FLU 002 Plus) (Completed)

			1056185 Respiratory Virus Hospitalization
			Study (FLU 003 Plus) (Recruiting)

			533741 SARS Coronavirus Vaccine
			(SARS-CoV) (Withdrawn)

			523276 SARS Survivor Evaluations (Withdrawn)

			494624 Efficacy of Systemic Glucocorticoid in
			the Treatment of Wheezing in Children
			(Unknown status)

			342524 Collection of Convalescent SARS
			Plasma by Apheresis (Completed)

			215826 Study of Alferon® LDO (Low Dose Oral)
			in Normal Volunteers (Completed)

			202239 [Occurrence of rota- and coronavirus
			as a cause of neonatal calf diarrhea in the
			Federal Republic of Germany].

			173576 Clinical Study of SARS in Children
			(Completed)

			173563 Induction of Cytokines in Human
			Monocytes by SARS-CoV in Adults and
			Children (Unknown status)

			172263 The Interaction Between
			Severe Acute Respiratory Distress Syndrome
			Viral Proteins and Monocytes (Withdrawn)

			99463 Phase I Study of a Vaccine for
			Severe Acute Respiratory Syndrome
			(SARS) (Completed)

			66209 Investigating
			Severe Acute Respiratory Syndrome
			(SARS) (Completed)

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